Understanding COVID-19 and the vaccine cold chain

Understanding COVID-19 and the vaccine cold chain

Understanding COVID-19 and the vaccine cold chain

B Medical Systems discusses the importance of reliable, high quality bio-medical storage and the crucial impact of the vaccine cold chain.
Optimal cold chain infrastructures are vital if vaccines are to reach healthcare facilities at temperatures where their efficacy remains unchanged. The COVID-19 pandemic has not only highlighted the disparities in vaccine roll outs around the world but the logistical hurdles that can arise when transporting and storing medical equipment at ultra-low temperatures. B Medical Systems offers a range of cold chain solutions that can be used to store and transport vital vaccines, medicines and samples around the world. Here, they tell Health Europa Quarterly (HEQ) about some of the key challenges in the vaccine cold chain and how their over ­40 years in operation have helped them become a global leader in providing cutting-edge medical devices.

What sets B Medical Systems’ refrigeration units apart from similar products on the market?

The main factor that sets B Medical Systems apart from other manufacturers out there is our history as experts in the provision of cold chain solutions for vaccines. During our 40 plus years of operations, we have gone through all the ups and downs of the industry; testing our equipment in the most rugged territories in the world. Our main business is in the vaccine cold chain in Africa, South America and Southeast Asia and the experiences that we gained from those areas flow into every product that we have.

What key challenges have you experienced related to transporting vaccines in inhospitable regions?

The main challenge is logistics. Most people will have a refrigerator at home but there are a lot of areas and households in the world that do not have access to power, and the same is true of medical facilities. How do you get a vaccine that is produced with the highest standards in some Western countries – be it Germany, the US, or the UK – to areas without the necessary facilities to keep vaccines stable and stored correctly?

Aside from storing the COVID-19 vaccine, what are some other existing or potential applications for ultra-low temperature freezers?

Any kind of current or future mRNA vaccine that needs or will need to be stored for a long period of time will require storage in an ULT freezer. This though would not be required for those vaccines that only need to be stored for up to two weeks, for instance, but certainly any biological specimen – human, animal and even plant specimens – that you want to store over a longer period need to be stored in an ULT.

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Supply Chain Creativity During COVID-19

Supply Chain Creativity During COVID-19

Supply Chain Creativity During COVID-19

Just as we typically don’t think about how groceries get to our grocery store, we probably don’t wonder how medical supplies get to our hospital room or doctor’s office. But for those of us who work in hospital supply chain management, we know a lot of negotiating, storage and coordination goes into this at the best of times.

As the world confronts COVID-19, issues regarding medical supply chains have been thrust into the spotlight. When a previously nonexistent health threat spreads across the globe in a matter of weeks, demand for essential medical equipment suddenly outstrips supply. Fraudulent vendors become a higher risk. Established vendor partnerships are strained. In fact, this virus originated near a major personal protective equipment (PPE) manufacturing area in China. This greatly reduced supply at a time when the world needed it most.

While most of UW Health has thus far not encountered a surge of COVID-19 patients, we have still faced unprecedented challenges since the onset of the pandemic. To overcome these current and potential shortages, serious creativity and collaboration need to be front and center.

With so much still unknown, a best-case scenario might be a new normal of carefully caring for COVID-19 patients in steady conjuncture with the many other patients who need our support. This creates a significant and prolonged increased need for PPE, posing tremendous challenges as the supply chain is under immense stress.

Using Public and Private Partnerships

As an academic medical center where our physicians are also faculty of the University of Wisconsin School of Medicine and Public Health, UW Health often works methodically. Now that time is of the essence, the health system and university have been collaborating closely and swiftly, and UW Health is benefiting greatly from its close partnership and proximity to the institution’s educators and students.

Making Unusable PPE Usable

In mid-March, UW Health received 1,250 hoods from the strategic national stockpile. These were meant to be used with our PAPRs, the respiratory protection systems that protect healthcare professionals when bodily fluids can be aerosolized, such as during intubation. Powered by a blower strapped around the wearer’s waist and connected by a hose to a hood covering the head, PAPRs offer the highest form of protection to a medical professional’s head, face and respiratory system during high-risk procedures.

Keeping Hand Sanitizer Flowing

As COVID-19 rapidly spread, the supply of hand sanitizer dwindled everywhere. We knew we would be hard-pressed to safely care for patients without it, so again we relied on the ingenuity and expertise of partners, this time at the UW-Madison School of Pharmacy’s Zeeh Pharmaceutical Experiment, which typically focuses on supporting drug development.

Reuse and Recycle

Sometimes supply chain challenges are not about getting or making more, but making existing supplies go further. We began sterilizing used N-95 respirators to reuse if we experienced a significant surge of patients. We have not yet needed to use them, but preparing for the worst is vital.

UW Health goes through thousands of surgical, isolation and patient gowns each week. Sourcing new, disposable gowns would be nearly impossible in the current climate. Fortunately, we are part of a laundry cooperative that not only launders all linens but sterilizes surgical and isolation gowns. Partnerships like this put a health system in a better position to control the supply chain than if it were a contracted client to a third-party laundry vendor or disposable gown supplier.

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Using Blockchain to Secure the Medical Supply Chain

Imperial Logistics leverages One Network’s Real Time Value Network cloud solution to manage the entire distribution process and help ensure the delivery of clean drugs to patients using Blockchain.

One Network Enterprises, the global provider of multi-party digital network platform and services, has announced that leading logistics provider Imperial Logistics is using One Network’s cloud platform to provide an end-to-end fulfillment backbone that manages the entire distribution process of essential medical supplies.

The solution includes serialization and authentication of critical drugs such as antimalarial medications.

By establishing One Network’s Real Time Value Network™ (RTVN) and serialization and tracking solutions for country-wide fulfillment, Imperial Logistics is safeguarding the distribution of medication.

The solutions enable Imperial Logistics to increase visibility and security throughout the global pharmaceutical manufacturing and supply chain process.

“Counterfeit or contaminated medication that contains the wrong or no active ingredients has long plagued the global, pharmaceutical supply chain. New regulations are coming into effect around the globe and mandates such as mass serialization and ‘track-and-trace’ are quickly becoming the worldwide standard for regulators,” said Dr. Iain Barton, Healthcare Strategy Executive at Imperial Logistics.

RTVN’s chain-of-custody and serialization authentication capabilities enable Imperial Logistics to track the control, transfer, management, and distribution of antiretroviral and antimalarial medication and supplies in real time, as they flow throughout the supply chain all the way to the individual patient.

The solution will also be used to comply with incoming national regulations in South Africa and other countries.

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Artificial Intelligence: The next big thing in Supply Chain Management

Imagine the endless possibilities of learning from 2.5 quintillion bytes of data generated every day. Artificial intelligence (AI), which began its journey 60 years ago is well on its course to make this implausible scenario a reality. Artificial Intelligence, is slowly taking over our lives.

From personal assistants like Siri in Apple products to stock trading to medical diagnosis, AI is able to learn from seemingly unstructured data, take decisions and perform actions in a way previously unimagined.

Businesses too are undergoing digitization rapidly. They are using AI – capable of performing tasks normally requiring human intelligence – to create a significant impact in the way businesses operate. In an increasingly dynamic environment comprising demanding customers and the need for speed, it was only a matter of time before the businesses embraced AI to obtain much needed agility. According to Accenture’s Technology Vision 2016 survey spanning 11 countries and 12 industries, 70 percent of corporate executives said they are significantly increasing investments in AI.

Artificial Intelligence in Supply Chain

Organizations are increasingly digitizing their supply chains to differentiate and drive revenue growth. According to Accenture’s digital operations survey 85 percent of organizations have adopted/ will adopt digital technologies in their supply chain within 1 year.

The key implication of this change is that the supply chains are generating massive amounts of data. AI is helping organizations analyze this data, gain a better understanding of the variables in the supply chain and helping them anticipate future scenarios. Thus, the use of AI in supply chains is helping businesses innovate rapidly by reducing the time to market and evolve by establishing an agile supply chain capable of foreseeing and dealing with uncertainties.

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