Transforming cold chain performance and management in lower-income countries

Transforming cold chain performance and management in lower-income countries

Transforming cold chain performance and management in lower-income countries

In many countries, one of the common factors limiting full and equitable access to effective immunization is the existence of gaps in cold chain and logistics (CCL) systems. This article focuses on the critical contribution that better management of CCL performance can make in addressing these barriers, as well as some essential practices needed to achieve and sustain these gains. These include (i) an emphasis on continuous improvement in CCL performance indicators, (ii) strong coordination and accountability across multiple stakeholders, and (iii) making the most of limited financial resources.

This article is informed by the Clinton Health Access Initiative’s (CHAI’s) experience working with National Immunization Programs (NIPs) and immunization partners to improve the effectiveness and efficiency of CCL systems (including CCE deployment and maintenance, temperature monitoring and control, stock management and distribution) across ten Gavi-supported “focus” countries.

1. Introduction

Vaccines can dramatically reduce morbidity and mortality from many serious diseases [1], and have a high return on investment [2].1 Unfortunately, gaps in vaccine cold chain and logistics (CCL) systems are one of the common factors limiting full and equitable access to the benefits of immunization. This is because such gaps undermine the availability and potency of vaccines at the point of administration, prevent the introduction of new life-saving vaccines, and waste precious human and financial resources [3].

2. Section I: Targeting CCL performance

The vaccines CCL system is considered to be performing well when (i) the full schedule of antigens is consistently available to serve the target population, (ii) in potent condition, (iii) at an affordable cost, and (iv) with a CCL network of sufficient capacity and reach to meet current and upcoming NIP goals (e.g., new vaccine introductions) [5].

3. Section II: Three key management practices to maximize CCL performance

Once programs appropriately target CCL performance, three management practices are critical to achieve effective and sustained improvements in these KPIs.

  • 3.1. From “firefighting” to continuous improvement
  • 3.2. Better coordination and accountability
  • 3.3. Making the most of limited resources

4. Conclusion

Investing in improved CCL management is crucial to sustainably improve CCL performance and provide the maximum benefit to immunization programs. As detailed above, success will require CCL management to focus on continuously improving CCL performance, have strong coordination and accountability, and make the most of the limited resources available.

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How a pharmaceutical supply chain company is taking advantage of the Internet of Things

In 2014, during a routine check from the Ministry of Health in the U.S., it was found that only 55 percent of vaccines were stored and transported in the temperature conditions that ensured the medication maintained its quality. To put that into perspective, every baby born receives vaccines to prevent diseases such as small pox and measles. If only 55 percent of those vaccinations maintain safety requirements, that creates a situation where a majority of babies don’t get the quality dosage and medication they need to protect them from diseases.

To overcome this challenge, organizations are turning to technology. More specifically, the Internet of Things (IoT) is making it possible to ensure the safer transportation and delivery of medications. Dutch pharmaceutical services company, AntTail, is paving the way for building innovative IoT applications that more effectively track the conditions of medications while in transit.

The team at AntTail built an IoT application using the Mendix low-code application development platform. The application collects sensor data from medication shipments to provide information on temperature, as well as send push notifications to patients with reminders on when to take the medication.

One of the barriers for creating IoT apps is the requirement of many disparate technologies. AntTail uses a central router as a hub for all of the sensors, collecting the data when there is a connection and storing the data when there is no connection to ensure that no data is lost. The Router uses Vodafone’s Managed IoT Connectivity Platform as a way to connect to AWS, and has a Java service running that puts the data into Hadoop.

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